Download for free books pdf Electrophysiology of Unconventional Channels and Pores 9783319201481 in English DJVU FB2 iBook by Anne H Delcour

Electrophysiology of Unconventional Channels and Pores

Electrophysiology of Unconventional Channels and Pores

by Anne H Delcour

Publisher: Springer International Publishing
ISBN: 9783319201481
Pages: 385
Format: pdf, ePub, mobi, fb2
File size: 10 Mb
Date posting: 2021-01-19


This book is dedicated to the channels and pores that belong to an eclectic and ubiquitous class of unconventional - perhaps at times strange - pore-forming molecules, which nevertheless play fundamental roles in various organisms. These non-canonical channels may take on various and sometimes complex architectures, such as large beta-barrels or lipid-containing pores. They may originate from bacteria, viruses or intracellular organelles. For some of them, the physiologically relevant substrate may indeed be ions, and for others folded polypeptides. Some are released by cells in a soluble form that has the ability to insert into biological membranes to exert its permeabilizing effect. Many of these unconventional pores have been investigated by electrophysiology, which, by its virtue of focusing on a few or even a single unit, has provided invaluable insight into the mechanisms and structure-function relationships of these remarkable membrane entities. The chapters of this book highlight a representative set of these interesting investigations.